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Challenges ahead

It is important to emphasise that while many technical aspects have been successfully addressed, several major issues need to be considered before paratransgenesis can be implemented. One key issue is to devise means to effectively introduce the engineered bacteria into mosquitoes in the field. One possible approach that is beginning to be explored is to place baiting stations (cotton balls soaked with sugar and bacteria and placed in clay jars) around villages where malaria is prevalent. Other major topics that need to be addressed are the resolution of regulatory, ethical and social issues related to the release of genetically modified bacteria in nature.


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