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Additional NAD Research, Inc., Partnership Studies Underway or Planned

A second study by NAD Research, Inc., led by Susan Broom, examined the response to IV NAD+ treatment in previous patients seeking treatment for alcohol addiction, opiate addiction, and neurodegenerative disease. Armed with baselines from the pharmacokinetic studies, we are examining whether the NAD+ treatment delivered the anticipated increase in plasma NAD+ and its metabolites. Preliminary findings are promising, and final results are expected in 2019.

We are also working to establish collaborative relationships with other researchers. A recent example involves a study by the Center of Magnetic Resonance Research at the University of Minnesota Medical School to measure NAD/NADH ratios in the brain utilizing a powerful MRI technique (In Vivo NAD+ Assay - Minn MRI Study). This study, which involved but a single individual, showed a dramatic increase in ATP production from a single dose of intravenous NAD+. We are currently designing an IRB-approved study to evaluate the cellular energy levels in the brains of additional healthy volunteers following a single dose of IV NAD+.

The implications of this study could be profound. In addition to validating the clinical results we see with intravenous NAD+ in detoxing addiction patients, a dramatic increase in brain cell energy levels could explain why Alzheimer’s patients show' improvement following intravenous NAD+ treatment and why we see such dramatic improvements in Parkinson’s, CTE, and TBI patients following intravenous NAD+.

The next clinical studies in the queue include examining the response of alcohol-addicted patients to IV NAD+ versus standard of care and examining the response of PTSD patients to IV NAD+. These studies are in the design phase and currently seeking funding.

NAD Research, Inc., is guided by a highly qualified Board of Advisors. Led by co-chairs, Dr. Krishna Doniparthi and Dr. Susan Broom, members include Dr. Ross Grant, Dr. Jade Berg, Dr. Jim Watson. Dr. Elizabeth Stuller. Dr. Ken Starr, Dr. Walker Dixon, Dr. Halland Chen, Dr. David Lefer, Dr. Tom Sharp, and Dr. Richard Mestayer.

Many paths for research have developed, and it is our hope that clinical findings regarding the myriad uses and strategies for positively impacting health by way of NAD+ will emerge. We have no doubt that there wall be more than three or four articles over the next 10 years.

References

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  • 12. Broom S.I., Carson J., Cook D., Hotard P, Mestayer R., Norris P, Simone K., Stuller E., Intravenous administration of nicotinamide adenine dinucleotide significantly reduces self-reported craving ratings associated with opiate and alcohol withdrawal. Society of Neuroscience Poster Presentation, 2014.
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