Home Economics American Trypanosomiasis Chagas Disease, Second Edition: One Hundred Years of Research
Parasitological and serological tests in the acute phase and reactivation
If negative and the clinical suspicion persists, try to collect further blood mainly during febrile peaks. If negative persist, ask for IgM antibodies, by IIF. If positive, decide with the clinician if the clinical picture, evolution and this result may justify etiological treatment.
Hints: Romana sign and other eventual portal of entry, will remain for several weeks. Conjunctivitis will disappear in few days. Differential diagnosis with visceral leishmaniasis should be made if negative parasitological results are obtained, mainly if the evolution of the patient is to a progressive worsening.
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