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Home arrow Computer Science arrow Computational Diffusion MRI: MICCAI Workshop, Athens, Greece, October 2016

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Investigation of the Neurite Density in the Visual Cortex

For the visual activity, Fig. 7 (top-left) depicts the group level neurite density map, Fig. 7 (top-right) the group level z-scores map stemming from the visual contrast and Fig. 7 (bottom) the corresponding group level Dice index map at the cortical area level (using the Destrieux’s parcellation [8]).

As we can see, the occipital lobe shows the highest values of the Dice indices and especially higher values on the right hemisphere compared to the left ones (the inferior occipital gyrus (O3) and associated sulcus, the lunate sulcus...). But

Group level maps for the visual contrast

Fig. 7 Group level maps for the visual contrast: (top-left) neurite density at the vertex level; (top- right) z-scores at the vertex level; (bottom) Dice index results at the cortical area level surprisingly, we found only few cortical areas significantly higher on the right hemisphere when we used a statistical t-test on the mean difference over all subjects (p-value < 5%). This can be explained by the fact that regarding the occipital lobe, the neurite density is highly asymmetrical whereas the functional activity is not. A recent work [14] established the complementary specialization regarding the language dominance and the visuospatial attention. In our case, as the right-handed population seem to all have a left-lateralized language network and as we saw the right-lateralization of the occipital lobe neurite density, we could explain our cortical asymmetries by thinking the visual network as a high neuron-dense path.

 
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